In the Albuquerque Journal today, there is an article titled "Genetic Curse: Deadly brain disease may be traced back to early N.M. settlers". It is estimated that 10,000 New Mexicans - who are descended from a certain old New Mexican family - carry the gene that causes cerebral cavenous malformation, or CCM. The disease can potentially cause brain damage in carriers. New Mexico has the largest concentration of cases in the world.
Certain carriers have researched their genealogy and have discovered common ancestors: Antonio Baca and Monica Duran y Chaves, who were married in Albuquerque in 1726. Personally, this couple are my 6th great-grandparents on my father's side.
To read more about this disease, click on this link. If you do not have a subscription to the Albuquerque Journal, click on "Trial Premium Pass". This will direct you to an advertisement that you will have to watch before you are able to access the article.